Our immune systems are designed to monitor for signs of foreign molecules, and among the first responses to such signals of potential danger are the formation of structures called inflammasomes.

But the innate immune system’s natural inflammatory reaction, a protective mechanism meant to tackle any impending infection or injury, may also cause damaging inflammation in people with a wide range of diseases in which that lingering response causes chronic health problems.

NodThera, one of a handful of companies developing drugs intended to inhibit inflammasomes without affecting appropriate immune system activity, has raised $55 million to advance its lead candidate through clinical… Read more »