Annexon Biosciences, a biotech founded in late 2014 by former Elan Pharmaceuticals executives, has added $100 million to its coffers to move its two clinical-stage programs along and to continue advancing its preclinical pipeline.

The South San Francisco-based company is developing drugs for patients with autoimmune and neurodegenerative disorders that are caused by an abnormal accumulation of the protein C1q. Typically the protein plays a key role in what’s known as the classical complement pathway, a part of the immune system. But when C1q builds up it can trigger a reaction that destroys synapses, leading to neurodegeneration.

Annexon’s C1q inhibitors are… Read more »